Formulation and Characterization of Solid Lipid Nanoparticles
نویسندگان
چکیده
منابع مشابه
Formulation and Physicochemical Characterization of Lycopene-Loaded Solid Lipid Nanoparticles.
PURPOSE Lycopene belongs to the carotenoids that shows good pharmacological properties including antioxidant, anti-inflammatory and anticancer. However, as a result of very low aqueous solubility, it has a limited systemic absorption, following oral administration. METHODS Here, we prepared a stable lycopene-loaded solid lipid nanoparticles using Precirol® ATO5, Compritol 888 ATO and myristic...
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Objective(s): In this work, Ginkgo biloba extract (GBE) loaded solid lipid nanoparticles (SLNs) were synthesized via high pressure homogenization method and their physicochemical properties, as well as cytotoxicity and antibacterial activities were evaluated.Methods: Ginkgo biloba extract SLNs (GBE-SLNs) were prepared using high pressure homogenization method. The morphology and size of S...
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BACKGROUND AND THE PURPOSE OF THE STUDY Domperidone (DOM) is a dopamine- receptor (D(2)) antagonist, widely used in the treatment of motion-sickness. The pharmacokinetic parameters of DOM make it a suitable candidate for development of Solid Lipid Nanoparticle (SLN) and Nanostructured Lipide Carrier (NLC). The purpose of the present investigation was to prepare and evaluate DOM loaded solid lip...
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Solid lipid nanoparticles are typically spherical with an average diameter between 1 and 1000 nm. It is an alternative carrier system to tradition colloidal carriers, such as, emulsions, liposomes, and polymeric micro and nanoparticles. Ramipril is an antihypertensive agent used in the treatment of hypertension. Its oral bioavailability is 28% and it is rapidly excreted through the renal route....
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Tuberculosis is an infectious disease caused by Mycobacterium Tuberculosis which attacks lungs and other parts of the body. Isoniazid is a hydrophilic drug that is having a first line antituberculosis drug. Entrapment Efficiency has been improved by preparing Solid Lipid Nanoparticles (SLNs). Two different variable Stearic acid and Tween 80 were used by using w/o/w double emulsion-solvent evapo...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Research
سال: 2013
ISSN: 2454-8405,0973-7200
DOI: 10.18579/jpcrkc/2013/12/4/79320